Vγ9Vδ2 T cells

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:gamma_delta_T_cell
T cell subtype
gptkbp:activatedBy microbial metabolites
bromohydrin pyrophosphate (BrHPP)
isopentenyl pyrophosphate (IPP)
gptkbp:compatibleWith MHC presentation for antigen recognition
gptkbp:cytotoxicTo tumor cells
infected cells
gptkbp:doesNotRecognize peptide antigens
gptkbp:expressedIn gptkb:NKG2D
gptkb:CD3
CD16
T cell receptor Vγ9
T cell receptor Vδ2
gptkbp:features primates
gptkbp:firstDescribed 1980s
gptkbp:foundIn lymphoid tissues
epithelial tissues
human peripheral blood
gptkbp:hasRole innate immunity
tumor surveillance
infection response
https://www.w3.org/2000/01/rdf-schema#label Vγ9Vδ2 T cells
gptkbp:involvedIn autoimmune diseases
inflammatory responses
antimicrobial defense
gptkbp:proportionOfTCells 1-10% in human peripheral blood
gptkbp:recognizedBy non-peptide antigens
phosphoantigens
gptkbp:secretes gptkb:interferon-gamma
gptkb:tumor_necrosis_factor-alpha
gptkbp:target immunotherapy research
gptkbp:bfsParent gptkb:CD277
gptkbp:bfsLayer 8