Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:alsoKnownAs |
Ullmann coupling
|
| gptkbp:application |
material science
organic synthesis pharmaceutical synthesis |
| gptkbp:catalyzes |
copper
|
| gptkbp:discoveredIn |
1901
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ullmann reaction
|
| gptkbp:improves |
ligand-assisted Ullmann reaction
microwave-assisted Ullmann reaction palladium-catalyzed coupling |
| gptkbp:limitation |
limited substrate scope
requires high temperature |
| gptkbp:namedAfter |
Fritz Ullmann
|
| gptkbp:product |
biaryl compound
|
| gptkbp:reactant |
copper
aryl halide |
| gptkbp:reactionCondition |
high temperature
inert atmosphere |
| gptkbp:reactionMechanism |
nucleophilic aromatic substitution
|
| gptkbp:relatedTo |
gptkb:Sonogashira_coupling
gptkb:Heck_reaction gptkb:Suzuki_coupling gptkb:Buchwald–Hartwig_amination |
| gptkbp:type |
coupling reaction
|
| gptkbp:bfsParent |
gptkb:Buchwald–Hartwig_amination
gptkb:Hartwig-Buchwald_coupling |
| gptkbp:bfsLayer |
7
|