Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
cross-coupling reaction |
| gptkbp:alternativeName |
gptkb:Buchwald-Hartwig_amination
|
| gptkbp:application |
material science
pharmaceutical synthesis |
| gptkbp:catalyzes |
nickel
palladium |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:field |
organic chemistry
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hartwig-Buchwald coupling
|
| gptkbp:ligand |
biaryl phosphine ligand
phosphine ligand |
| gptkbp:mechanismOfAction |
oxidative addition
reductive elimination transmetalation |
| gptkbp:namedAfter |
gptkb:John_F._Hartwig
gptkb:Stephen_L._Buchwald |
| gptkbp:product |
arylamine
|
| gptkbp:reactant |
amphetamine
aryl halide |
| gptkbp:relatedTo |
gptkb:Ullmann_reaction
gptkb:Suzuki_coupling |
| gptkbp:type |
C-N bond formation
|
| gptkbp:bfsParent |
gptkb:John_Hartwig
|
| gptkbp:bfsLayer |
6
|