Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
|
gptkbp:application |
material science
pharmaceutical synthesis |
gptkbp:basisFor |
potassium tert-butoxide
sodium tert-butoxide |
gptkbp:catalyzes |
nickel
palladium |
gptkbp:field |
organic chemistry
|
gptkbp:firstReported |
1994
|
https://www.w3.org/2000/01/rdf-schema#label |
Buchwald–Hartwig amination
|
gptkbp:importantFor |
widely used in organic synthesis
|
gptkbp:ligand |
phosphine ligand
|
gptkbp:mechanismOfAction |
palladium-catalyzed
|
gptkbp:namedAfter |
gptkb:John_F._Hartwig
gptkb:Stephen_L._Buchwald |
gptkbp:product |
aryl amine
|
gptkbp:reactant |
amphetamine
aryl halide |
gptkbp:relatedTo |
gptkb:Ullmann_reaction
gptkb:Suzuki_coupling |
gptkbp:solvent |
toluene
dioxane |
gptkbp:step |
oxidative addition
reductive elimination amine coordination |
gptkbp:type |
cross-coupling reaction
|
gptkbp:bfsParent |
gptkb:Stephen_Buchwald
gptkb:John_F._Hartwig gptkb:Stephen_L._Buchwald |
gptkbp:bfsLayer |
6
|