Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:topoisomerase_I
|
| gptkbp:catalyzes |
transient single-strand breaks
|
| gptkbp:EC_number |
5.99.1.2
|
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
relaxes supercoiled DNA
|
| gptkbp:GO_term |
GO:0003917
|
| gptkbp:inhibitedBy |
gptkb:camptothecin
|
| gptkbp:mechanismOfAction |
cuts one strand of DNA
|
| gptkbp:requires_ATP |
false
|
| gptkbp:role |
DNA repair
DNA replication DNA recombination DNA transcription |
| gptkbp:subspecies |
Type IA topoisomerase
Type IB topoisomerase Type IC topoisomerase |
| gptkbp:bfsParent |
gptkb:Topoisomerase
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Type I topoisomerase
|