Statements (21)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
gptkb:topoisomerase_I
|
gptkbp:catalyzes |
transient single-strand breaks
|
gptkbp:EC_number |
5.99.1.2
|
gptkbp:foundIn |
prokaryotes
eukaryotes |
gptkbp:function |
relaxes supercoiled DNA
|
gptkbp:GO_term |
GO:0003917
|
https://www.w3.org/2000/01/rdf-schema#label |
Type I topoisomerase
|
gptkbp:inhibitedBy |
gptkb:camptothecin
|
gptkbp:mechanismOfAction |
cuts one strand of DNA
|
gptkbp:requires_ATP |
false
|
gptkbp:role |
DNA repair
DNA replication DNA recombination DNA transcription |
gptkbp:subspecies |
Type IA topoisomerase
Type IB topoisomerase Type IC topoisomerase |
gptkbp:bfsParent |
gptkb:enzyme
|
gptkbp:bfsLayer |
5
|