Type I topoisomerase

GPTKB entity

Statements (21)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:topoisomerase_I
gptkbp:catalyzes transient single-strand breaks
gptkbp:EC_number 5.99.1.2
gptkbp:foundIn prokaryotes
eukaryotes
gptkbp:function relaxes supercoiled DNA
gptkbp:GO_term GO:0003917
https://www.w3.org/2000/01/rdf-schema#label Type I topoisomerase
gptkbp:inhibitedBy gptkb:camptothecin
gptkbp:mechanismOfAction cuts one strand of DNA
gptkbp:requires_ATP false
gptkbp:role DNA repair
DNA replication
DNA recombination
DNA transcription
gptkbp:subspecies Type IA topoisomerase
Type IB topoisomerase
Type IC topoisomerase
gptkbp:bfsParent gptkb:enzyme
gptkbp:bfsLayer 5