Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:discoveredIn |
2005
|
| gptkbp:distinctiveFeature |
Multi-protein Cascade complex
Presence of Cas3 |
| gptkbp:firstDescribed |
gptkb:Feng_Zhang
gptkb:Eugene_Koonin Kira Makarova |
| gptkbp:foundIn |
gptkb:Bacteria
Archaea |
| gptkbp:function |
Adaptive immunity
|
| gptkbp:hasComponent |
gptkb:Cas3_protein
gptkb:Cascade_complex |
| https://www.w3.org/2000/01/rdf-schema#label |
Type I CRISPR system
|
| gptkbp:mainEffector |
gptkb:Cas3
Cascade |
| gptkbp:mechanismOfAction |
DNA interference
|
| gptkbp:notableExample |
Escherichia coli Type I-E system
|
| gptkbp:requires |
Protospacer adjacent motif (PAM)
|
| gptkbp:role |
Bacterial defense
Genome editing research |
| gptkbp:subclassOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:subspecies |
Type I-A
Type I-B Type I-C Type I-D Type I-E Type I-F Type I-G |
| gptkbp:target |
Foreign DNA
|
| gptkbp:uses |
gptkb:Cas_proteins
gptkb:crRNA |
| gptkbp:bfsParent |
gptkb:CRISPR-Cas3
|
| gptkbp:bfsLayer |
8
|