Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
collagen |
gptkbp:component |
glomerular basement membrane
inner ear basement membrane lens capsule |
gptkbp:discoveredBy |
gptkb:Kefalides_NA
|
gptkbp:encodedBy |
gptkb:COL4A2_gene
gptkb:COL4A3_gene gptkb:COL4A4_gene gptkb:COL4A5_gene gptkb:COL4A6_gene gptkb:COL4A1_gene |
gptkbp:features |
forms sheet-like networks
non-fibrillar collagen |
gptkbp:form |
network-like structure
|
gptkbp:foundIn |
basement membrane
|
gptkbp:function |
structural support
filtration barrier |
https://www.w3.org/2000/01/rdf-schema#label |
Type IV collagen
|
gptkbp:molecularWeight |
~400 kDa
|
gptkbp:mutationAssociatedWith |
gptkb:Alport_syndrome
gptkb:Goodpasture_syndrome |
gptkbp:presentIn |
all metazoans
|
gptkbp:requires |
tissue development
organ function |
gptkbp:subunit |
gptkb:alpha-1(IV)_chain
gptkb:alpha-2(IV)_chain gptkb:alpha-3(IV)_chain gptkb:alpha-4(IV)_chain gptkb:alpha-5(IV)_chain gptkb:alpha-6(IV)_chain |
gptkbp:bfsParent |
gptkb:collagen
|
gptkbp:bfsLayer |
6
|