Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:CRISPR-Cas_system
|
gptkbp:application |
gptkb:biotechnology
genome editing gene regulation |
gptkbp:component |
gptkb:CRISPR_array
gptkb:Cas_genes gptkb:Cas9_protein gptkb:crRNA gptkb:tracrRNA |
gptkbp:contains |
gptkb:Cas9_protein
|
gptkbp:discoveredIn |
gptkb:Streptococcus_pyogenes
|
gptkbp:firstDescribed |
2012
|
gptkbp:function |
defense against foreign genetic elements
|
https://www.w3.org/2000/01/rdf-schema#label |
Type II CRISPR system
|
gptkbp:mechanismOfAction |
adaptive immune system in bacteria and archaea
|
gptkbp:notableFor |
basis for CRISPR-Cas9 genome editing technology
|
gptkbp:recognizedBy |
PAM sequence
|
gptkbp:requires |
gptkb:Cas9
gptkb:crRNA gptkb:tracrRNA |
gptkbp:subclassOf |
gptkb:CRISPR-Cas_system
|
gptkbp:uses |
single multidomain protein for interference
|
gptkbp:bfsParent |
gptkb:CRISPR/Cas9
|
gptkbp:bfsLayer |
6
|