Tryptophanyl-tRNA synthetase

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName TrpRS
tryptophan--tRNA ligase
tryptophanyl-transfer RNA synthetase
gptkbp:catalyzes attachment of tryptophan to tRNA(Trp)
gptkbp:cofactor Mg2+
gptkbp:EC_number 6.1.1.2
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function aminoacylation of tRNA(Trp)
gptkbp:gene WARS
gptkbp:gene_symbol_(E._coli) trpS
gptkbp:GO_term GO:0004820
https://www.w3.org/2000/01/rdf-schema#label Tryptophanyl-tRNA synthetase
gptkbp:inhibitedBy indolmycin
gptkbp:locatedIn gptkb:cytoplasm
gptkbp:OMIM 191100
gptkbp:participatedIn protein biosynthesis
gptkbp:PDB 1MAU
gptkbp:product gptkb:AMP
pyrophosphate
L-tryptophyl-tRNA(Trp)
gptkbp:proteinFamily gptkb:aminoacyl-tRNA_synthetase
gptkbp:requires translator
gptkbp:structure homodimer
gptkbp:substrate gptkb:ATP
L-tryptophan
tRNA(Trp)
gptkbp:UniProt_ID_(E._coli) gptkb:P00909
gptkbp:UniProtID P23381
gptkbp:bfsParent gptkb:TRYAR
gptkbp:bfsLayer 8