Tryptophan pyrrolase

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:tryptophan_2,3-dioxygenase
gptkbp:biologicalProcess dioxygenase activity
gptkbp:catalyzes oxidative cleavage of L-tryptophan
gptkbp:cofactor hemoglobin
gptkbp:discoveredBy gptkb:Hayaishi_Osamu
gptkbp:discoveredIn 1957
gptkbp:EC_number 1.13.11.11
gptkbp:foundIn mammals
liver
gptkbp:gene gptkb:TDO2
gptkbp:GO_term GO:0004833
https://www.w3.org/2000/01/rdf-schema#label Tryptophan pyrrolase
gptkbp:inhibitedBy inhibited by alpha-methyltryptophan
gptkbp:pathway kynurenine pathway
gptkbp:product N-formylkynurenine
gptkbp:regulates induced by glucocorticoids
induced by tryptophan
gptkbp:substrate L-tryptophan
gptkbp:UniProtID P48775 (human)
gptkbp:bfsParent gptkb:TDO2
gptkbp:bfsLayer 7