Transposition of the great arteries

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:atrial_septal_defect gptkb:disease
gptkbp:affects	heart newborns
gptkbp:alsoKnownAs	gptkb:TGA
gptkbp:associatedWith	gptkb:atrial_septal_defect gptkb:patent_ductus_arteriosus gptkb:ventricular_septal_defect
gptkbp:canBeDetectedPrenatally	yes
gptkbp:cause	cyanosis shortness of breath poor feeding in infants
gptkbp:complication	gptkb:arrhythmia heart failure growth retardation
gptkbp:diagnosedBy	echocardiogram
gptkbp:field	pediatric cardiology
gptkbp:firstDescribed	1797
gptkbp:hasAbnormality	aorta arises from right ventricle pulmonary artery arises from left ventricle
https://www.w3.org/2000/01/rdf-schema#label	Transposition of the great arteries
gptkbp:ICD-10_code	Q20.3
gptkbp:MeSH_ID	D014180
gptkbp:mortalityRate	high without intervention low with modern surgery
gptkbp:OMIM	608808
gptkbp:prevalence	about 1 in 3,500-5,000 live births
gptkbp:prognosisWithoutTreatment	poor
gptkbp:prognosisWithTreatment	good
gptkbp:requiresImmediateAttentionAtBirth	yes
gptkbp:riskFactor	maternal diabetes maternal rubella infection maternal age over 40
gptkbp:subspecies	gptkb:dextro-Transposition_of_the_great_arteries_(d-TGA) gptkb:levo-Transposition_of_the_great_arteries_(l-TGA)
gptkbp:symptom	rapid breathing clubbing of fingers and toes
gptkbp:treatment	gptkb:balloon_atrial_septostomy gptkb:prostaglandin_E1 surgery arterial switch operation
gptkbp:bfsParent	gptkb:TGA
gptkbp:bfsLayer	6