Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:atrial_septal_defect
medical condition |
| gptkbp:affects |
newborns
premature infants |
| gptkbp:affectsOrgan |
heart
lungs |
| gptkbp:cause |
heart failure
endocarditis pulmonary hypertension |
| gptkbp:causedBy |
failure of ductus arteriosus to close after birth
|
| gptkbp:complication |
congestive heart failure
infective endocarditis pulmonary overcirculation |
| gptkbp:diagnosedBy |
gptkb:chest_X-ray
echocardiogram cardiac catheterization |
| gptkbp:firstDescribed |
Galen
|
| gptkbp:hasEpidemiology |
more common in females
more common in premature infants |
| gptkbp:hasStandardOfCare |
medical or surgical closure
|
| gptkbp:hasTreatmentGoal |
closure of ductus arteriosus
|
| https://www.w3.org/2000/01/rdf-schema#label |
patent ductus arteriosus
|
| gptkbp:ICD-10_code |
Q25.0
|
| gptkbp:inheritance |
sporadic
rarely familial |
| gptkbp:MeSH_ID |
D004374
|
| gptkbp:namedAfter |
gptkb:ductus_arteriosus
|
| gptkbp:OMIM |
604051
|
| gptkbp:pathology |
left-to-right shunt
increased pulmonary blood flow persistent patency of ductus arteriosus after birth |
| gptkbp:prevalence |
1 in 2000 live births
|
| gptkbp:prognosis |
good with treatment
|
| gptkbp:riskFactor |
gptkb:congenital_rubella_infection
female sex high altitude birth prematurity |
| gptkbp:symptom |
shortness of breath
failure to thrive heart murmur poor feeding |
| gptkbp:synonym |
gptkb:personal_computer
gptkb:persistent_ductus_arteriosus |
| gptkbp:treatment |
gptkb:ibuprofen
indomethacin catheter-based closure surgical ligation |
| gptkbp:bfsParent |
gptkb:Transposition_of_the_great_arteries
gptkb:Congenital_Malformations_of_the_Heart gptkb:Congenital_heart_disease |
| gptkbp:bfsLayer |
7
|