dextro-Transposition of the great arteries (d-TGA)
GPTKB entity
Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:atrial_septal_defect
gptkb:disease |
| gptkbp:affects |
newborns
|
| gptkbp:alsoKnownAs |
complete transposition of the great arteries
d-TGA |
| gptkbp:associatedWith |
gptkb:NKX2-5
gptkb:GATA4 MED13L CFC1 ZIC3 |
| gptkbp:cause |
cyanosis
hypoxemia |
| gptkbp:complication |
gptkb:arrhythmia
heart failure pulmonary hypertension coronary artery problems |
| gptkbp:diagnosedBy |
echocardiogram
fetal ultrasound |
| gptkbp:field |
cardiology
pediatric cardiology |
| gptkbp:firstDescribed |
1887
|
| gptkbp:hasAnatomicalFeature |
aorta arises from right ventricle
pulmonary artery arises from left ventricle patent ductus arteriosus (sometimes present) patent foramen ovale (sometimes present) ventricular septal defect (sometimes present) |
| gptkbp:hasHistoricalTreatment |
Mustard procedure
Senning procedure |
| gptkbp:hasOrphanetID |
997
|
| gptkbp:hasTreatmentOutcome |
over 90% survival with surgery
|
| https://www.w3.org/2000/01/rdf-schema#label |
dextro-Transposition of the great arteries (d-TGA)
|
| gptkbp:ICD-10_code |
Q20.3
|
| gptkbp:MeSH_ID |
D014162
|
| gptkbp:OMIM |
608808
|
| gptkbp:prevalence |
about 1 in 4000 live births
|
| gptkbp:prognosis |
fatal without treatment
good with surgery |
| gptkbp:riskFactor |
genetic factors
maternal diabetes maternal rubella infection maternal age over 40 |
| gptkbp:symptom |
blue skin
failure to thrive rapid breathing poor feeding |
| gptkbp:treatment |
gptkb:balloon_atrial_septostomy
arterial switch operation prostaglandin E1 infusion |
| gptkbp:bfsParent |
gptkb:Transposition_of_the_great_arteries
|
| gptkbp:bfsLayer |
7
|