Thyroid Carcinoma

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:affectsOrgan gptkb:Thyroid_gland
gptkbp:associatedWith gptkb:RAS_mutation
gptkb:Multiple_endocrine_neoplasia_type_2
gptkb:Hashimoto's_thyroiditis
BRAF mutation
RET proto-oncogene mutation
gptkbp:diagnosedBy Ultrasound
Fine needle aspiration biopsy
Thyroid scan
gptkbp:firstDescribed 19th century
gptkbp:hasEpidemiology More common in adults
Most common endocrine malignancy
Rare in children
gptkbp:hasMetastasisSite gptkb:Bones
Lungs
Lymph nodes
gptkbp:hasScreeningTest Thyroid function tests
Neck ultrasound
https://www.w3.org/2000/01/rdf-schema#label Thyroid Carcinoma
gptkbp:ICD-10_code gptkb:C73
gptkbp:incidence About 1% of all cancers
Most common in ages 30-60
gptkbp:mortalityRate High for anaplastic type
Low for differentiated types
gptkbp:prevalence Incidence increasing worldwide
More common in women
gptkbp:prognosis Generally good for papillary and follicular types
Poor for anaplastic type
gptkbp:riskFactor Family history
Radiation exposure
Iodine deficiency
gptkbp:stageName gptkb:TNM_staging
gptkbp:subspecies gptkb:Medullary_thyroid_carcinoma
Anaplastic thyroid carcinoma
Follicular thyroid carcinoma
Papillary thyroid carcinoma
gptkbp:symptom Difficulty swallowing
Hoarseness
Neck lump
Neck pain
gptkbp:treatment Surgery
Chemotherapy
External beam radiation therapy
Radioactive iodine therapy
Thyroid hormone therapy
gptkbp:bfsParent gptkb:D014842
gptkbp:bfsLayer 6