|
gptkbp:instanceOf
|
gptkb:chemical_compound
herbicide
anthelmintic
|
|
gptkbp:ATCCode
|
P02CC01
|
|
gptkbp:Bioavailability
|
100% (oral)
|
|
gptkbp:CASNumber
|
148-79-8
|
|
gptkbp:category
|
Fungicide
World Health Organization essential medicine
Anthelmintic
Antifungal agent
Benzimidazole
Human drug
Pesticide
Thiazole
Veterinary drug
|
|
gptkbp:chemicalFormula
|
C10H7N3S
|
|
gptkbp:Developed_by
|
gptkb:Merck_&_Co.
|
|
gptkbp:Discovered_in
|
1961
|
|
gptkbp:Elimination_half-life
|
1.2 hours
|
|
gptkbp:Excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Thiabendazole
|
|
gptkbp:IUPACName
|
2-(1,3-thiazol-4-yl)-1H-benzimidazole
|
|
gptkbp:Legal_status_(US)
|
prescription only
|
|
gptkbp:Mechanism_of_action
|
inhibits fumarate reductase
|
|
gptkbp:meltingPoint
|
304–305 °C
|
|
gptkbp:Metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
201.25 g/mol
|
|
gptkbp:Pregnancy_category_(US)
|
C
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1431
5430
DB00730
|
|
gptkbp:Related_compound
|
gptkb:fenbendazole
gptkb:albendazole
gptkb:mebendazole
oxfendazole
|
|
gptkbp:Routes_of_administration
|
oral
topical
|
|
gptkbp:Side_effect
|
nausea
vomiting
dizziness
allergic reactions
|
|
gptkbp:Solubility_in_water
|
50 mg/L at 25 °C
|
|
gptkbp:UNII
|
0323TZZ3EC
|
|
gptkbp:Used_as
|
postharvest fungicide
|
|
gptkbp:Used_to_treat
|
trichinosis
strongyloidiasis
cutaneous larva migrans
|
|
gptkbp:bfsParent
|
gptkb:TBZ
gptkb:E233
|
|
gptkbp:bfsLayer
|
7
|