albendazole

GPTKB entity

Statements (60)
Predicate Object
gptkbp:instanceOf anthelmintic drug
gptkbp:administeredBy animals
humans
gptkbp:affiliatedWith benzimidazole
gptkbp:approvalYear 1975
gptkbp:ATCCode P02CA03
gptkbp:bioavailability low (increased with fatty meal)
gptkbp:brand gptkb:Zentel
gptkb:Albenza
gptkb:Andazol
gptkb:Eskazole
gptkb:Valbazen
gptkbp:CASNumber 54965-21-8
gptkbp:chemicalFormula C12H15N3O2S
gptkbp:contraindication gptkb:liver_disease
pregnancy
gptkbp:discoveredBy GlaxoSmithKline
gptkbp:eliminationHalfLife 8.5 hours
gptkbp:excretion urine
bile
feces
https://www.w3.org/2000/01/rdf-schema#label albendazole
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction binds to beta-tubulin
inhibits microtubule polymerization
gptkbp:metabolism liver
albendazole sulfone
albendazole sulfoxide
gptkbp:pregnancyCategory C (US)
gptkbp:proteinBinding 70%
gptkbp:PubChem_CID 2082
DB00518
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
vomiting
abdominal pain
dizziness
headache
hair loss
elevated liver enzymes
bone marrow suppression
gptkbp:UNII F4216019LN
gptkbp:usedFor treatment of strongyloidiasis
treatment of ascariasis
treatment of cutaneous larva migrans
treatment of filariasis
treatment of giardiasis
treatment of hookworm infection
treatment of hydatid disease
treatment of neurocysticercosis
treatment of parasitic worm infestations
treatment of pinworm infection
treatment of toxocariasis
treatment of trichuriasis
gptkbp:WHOModelListOfEssentialMedicines yes
gptkbp:bfsParent gptkb:Ascaris_lumbricoides
gptkb:Trichinella_spiralis
gptkb:Wuchereria_bancrofti
gptkb:raccoon_roundworm
gptkbp:bfsLayer 5