|
gptkbp:instanceOf
|
gptkb:chemical_compound
anthelmintic drug
|
|
gptkbp:approvedBy
|
1971
|
|
gptkbp:ATCCode
|
P02CA01
|
|
gptkbp:bioavailability
|
poor (oral)
|
|
gptkbp:CASNumber
|
31431-39-7
|
|
gptkbp:discoveredBy
|
gptkb:Janssen_Pharmaceutica
|
|
gptkbp:eliminationHalfLife
|
2.5–5.5 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:hasMolecularFormula
|
C16H13N3O3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mebendazole
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits microtubule synthesis
|
|
gptkbp:meltingPoint
|
288–292 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
3891
4030
CHEMBL685
DB00643
|
|
gptkbp:relatedTo
|
gptkb:albendazole
gptkb:thiabendazole
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
diarrhea
abdominal pain
rash
|
|
gptkbp:synonym
|
gptkb:Antiox
gptkb:Vermox
Telmin
|
|
gptkbp:UNII
|
81G40H8B0T
|
|
gptkbp:usedFor
|
treatment of helminth infections
treatment of hookworm
treatment of pinworm
treatment of roundworm
treatment of whipworm
|
|
gptkbp:bfsParent
|
gptkb:Ascaris_lumbricoides
gptkb:Trichinella_spiralis
|
|
gptkbp:bfsLayer
|
5
|