Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:SRY_protein
|
| gptkbp:biologicalProcess |
transcription factor
|
| gptkbp:compatibleWith |
females
|
| gptkbp:discoveredBy |
gptkb:Peter_Goodfellow
|
| gptkbp:discoveredIn |
1990
|
| gptkbp:encodedBy |
gptkb:SRY_gene
|
| gptkbp:Entrez_Gene_ID |
6736
|
| gptkbp:expressedIn |
early embryonic development
|
| gptkbp:foundIn |
mammals
|
| gptkbp:function |
initiates male sex determination
triggers development of testes |
| https://www.w3.org/2000/01/rdf-schema#label |
Testis-determining factor
|
| gptkbp:locatedOnChromosome |
gptkb:Y_chromosome
|
| gptkbp:motif |
HMG-box
|
| gptkbp:mutationAssociatedWith |
can cause Swyer syndrome
can cause sex reversal |
| gptkbp:OMIM |
480000
|
| gptkbp:orthologIn |
mouse Sry protein
|
| gptkbp:regulates |
gptkb:SOX9_gene
|
| gptkbp:role |
gonadal differentiation
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:UniProtID |
gptkb:Q05066
|
| gptkbp:bfsParent |
gptkb:P60033
|
| gptkbp:bfsLayer |
8
|