|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
TAS2Rs
bitter taste receptors
|
|
gptkbp:associatedWith
|
phenylthiocarbamide (PTC) tasting
propylthiouracil (PROP) tasting
|
|
gptkbp:discoveredIn
|
early 2000s
|
|
gptkbp:encodedBy
|
TAS2R genes
|
|
gptkbp:expressedIn
|
gastrointestinal tract
tongue
airways
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
detect bitter compounds
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Taste2 GPCRs
|
|
gptkbp:ligand
|
bitter compounds
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
gptkb:chromosome_5
gptkb:chromosome_12
|
|
gptkbp:location
|
taste receptor cells
|
|
gptkbp:notableMember
|
TAS2R14
TAS2R16
TAS2R38
|
|
gptkbp:numberOfGenes
|
25-30
|
|
gptkbp:orthologIn
|
rodents
primates
other vertebrates
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptors
|
|
gptkbp:relatedTo
|
Taste1 GPCRs
|
|
gptkbp:role
|
toxin avoidance
food selection
|
|
gptkbp:structure
|
seven transmembrane domains
|
|
gptkbp:type
|
G protein-mediated pathway
|
|
gptkbp:variant
|
bitter taste sensitivity
|
|
gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptor_superfamily
|
|
gptkbp:bfsLayer
|
7
|