TRiC complex

GPTKB entity

Statements (44)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs CCT complex
chaperonin containing TCP-1
gptkbp:associatedWith gptkb:cancer
neurodegenerative diseases
gptkbp:biologicalProcess protein folding
ATPase activity
prevention of protein aggregation
unfolded protein binding
gptkbp:compatibleWith gptkb:Bacteria
archaea (as TRiC)
gptkbp:component gptkb:CCT6A
gptkb:CCT1
gptkb:CCT2
gptkb:CCT3
gptkb:CCT4
gptkb:CCT5
gptkb:CCT7
gptkb:CCT8
CCT6B
gptkbp:discoveredBy gptkb:John_Ellis
gptkbp:discoveredIn 1992
gptkbp:foundIn eukaryotic cells
gptkbp:function protein folding
gptkbp:GO_term GO:0005832
https://www.w3.org/2000/01/rdf-schema#label TRiC complex
gptkbp:orthologIn archaeal thermosome
gptkbp:PDB 5GW4
gptkbp:regulates ATP binding and hydrolysis
gptkbp:relatedTo molecular chaperone
Group II chaperonin
gptkbp:requires cell viability
gptkbp:reviewedBy gptkb:Nature_Reviews_Molecular_Cell_Biology
Cell
gptkbp:structure double-ring
eight different subunits per ring
gptkbp:subcellularLocation cytosol
gptkbp:substrate gptkb:actin
tubulin
WD40 repeat proteins
cell cycle proteins
gptkbp:UniProtID P80314
gptkbp:bfsParent gptkb:CCT_(gene)
gptkbp:bfsLayer 7