gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alsoKnownAs
|
CCT complex
chaperonin containing TCP-1
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
gptkbp:biologicalProcess
|
protein folding
ATPase activity
prevention of protein aggregation
unfolded protein binding
|
gptkbp:compatibleWith
|
gptkb:Bacteria
archaea (as TRiC)
|
gptkbp:component
|
gptkb:CCT6A
gptkb:CCT1
gptkb:CCT2
gptkb:CCT3
gptkb:CCT4
gptkb:CCT5
gptkb:CCT7
gptkb:CCT8
CCT6B
|
gptkbp:discoveredBy
|
gptkb:John_Ellis
|
gptkbp:discoveredIn
|
1992
|
gptkbp:foundIn
|
eukaryotic cells
|
gptkbp:function
|
protein folding
|
gptkbp:GO_term
|
GO:0005832
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRiC complex
|
gptkbp:orthologIn
|
archaeal thermosome
|
gptkbp:PDB
|
5GW4
|
gptkbp:regulates
|
ATP binding and hydrolysis
|
gptkbp:relatedTo
|
molecular chaperone
Group II chaperonin
|
gptkbp:requires
|
cell viability
|
gptkbp:reviewedBy
|
gptkb:Nature_Reviews_Molecular_Cell_Biology
Cell
|
gptkbp:structure
|
double-ring
eight different subunits per ring
|
gptkbp:subcellularLocation
|
cytosol
|
gptkbp:substrate
|
gptkb:actin
tubulin
WD40 repeat proteins
cell cycle proteins
|
gptkbp:UniProtID
|
P80314
|
gptkbp:bfsParent
|
gptkb:CCT_(gene)
|
gptkbp:bfsLayer
|
7
|