Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:CD40
|
| gptkbp:associatedWith |
autoimmune diseases
immunodeficiency lymphomas |
| gptkbp:discoveredBy |
gptkb:Edward_A._Clark
|
| gptkbp:encodes |
CD40 protein
|
| gptkbp:Entrez_Gene_ID |
958
ENSG00000101017 |
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells macrophages endothelial cells |
| gptkbp:function |
B cell activation
immune response regulation T cell-dependent immunoglobulin class switching |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
11919
|
| https://www.w3.org/2000/01/rdf-schema#label |
TNFRSF5
|
| gptkbp:interactsWith |
CD40 ligand (CD40L, CD154)
|
| gptkbp:locatedOnChromosome |
chromosome 20
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:mutationAssociatedWith |
Hyper-IgM syndrome type 3
|
| gptkbp:OMIM |
109535
|
| gptkbp:orthologInMouse |
Cd40
|
| gptkbp:UniProtID |
P25942
|
| gptkbp:bfsParent |
gptkb:CD40
gptkb:TNFRSF gptkb:TRAF1 gptkb:TRAF5 |
| gptkbp:bfsLayer |
8
|