TAp63

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy DNA damage
gptkbp:alternativeSplicing gptkb:TP63_gene
gptkbp:discoveredIn 1998
gptkbp:domain DNA-binding domain
oligomerization domain
transactivation domain
gptkbp:encodedBy gptkb:TP63_gene
gptkbp:expressedIn epithelial tissues
oocytes
gptkbp:function tumor suppressor
transcription factor
gptkbp:hasIsoform gptkb:p63
https://www.w3.org/2000/01/rdf-schema#label TAp63
gptkbp:inhibitedBy gptkb:ΔNp63
gptkbp:memberOf gptkb:p53_protein_family
gptkbp:orthologIn mouse TAp63
gptkbp:regulates apoptosis
cell cycle arrest
epithelial development
gptkbp:role female germline quality control
prevention of premature ovarian failure
gptkbp:bfsParent gptkb:p63
gptkbp:bfsLayer 6