|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:TDP-43
|
|
gptkbp:associatedWith
|
amyotrophic lateral sclerosis
frontotemporal dementia
|
|
gptkbp:discoveredBy
|
gptkb:Jean-Pierre_Julien
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:domain
|
RNA recognition motif
glycine-rich domain
|
|
gptkbp:encodedBy
|
gptkb:TARDBP_gene
|
|
gptkbp:form
|
inclusions in neurodegenerative diseases
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
DNA-binding
RNA-binding
|
|
gptkbp:HGNC_ID
|
11574
|
|
gptkbp:involvedIn
|
RNA splicing
transcriptional repression
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p36.22
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:OMIM
|
605078
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
4IUF
|
|
gptkbp:postTranslationalModification
|
phosphorylation
cleavage
ubiquitination
|
|
gptkbp:RefSeq
|
NP_031401.1
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:Q13148
|
|
gptkbp:bfsParent
|
gptkb:TDP-43
gptkb:TDP43
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TAR DNA-binding protein
|