Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
neurodevelopmental disorders
|
| gptkbp:binds |
gptkb:calcium_ion
phospholipid membrane |
| gptkbp:discoveredBy |
gptkb:Thomas_C._Südhof
|
| gptkbp:domain |
gptkb:C2A_domain
gptkb:C2B_domain |
| gptkbp:encodedBy |
SYT1 gene
|
| gptkbp:Entrez_Gene_ID |
6857
|
| gptkbp:expressedIn |
brain
neurons |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
calcium sensor for synaptic vesicle exocytosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
Synaptotagmin-1
|
| gptkbp:interactsWith |
gptkb:SNAP-25
gptkb:SNARE_complex gptkb:syntaxin-1 gptkb:synaptobrevin |
| gptkbp:involvedIn |
neurotransmitter release
|
| gptkbp:locatedIn |
presynaptic vesicle membrane
|
| gptkbp:locatedOnChromosome |
12q21.2
|
| gptkbp:molecularWeight |
47 kDa
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster |
| gptkbp:PDB |
1BYN
|
| gptkbp:UniProtID |
P21579
|
| gptkbp:bfsParent |
gptkb:SYT1
gptkb:Synaptotagmin |
| gptkbp:bfsLayer |
7
|