|
gptkbp:instanceOf
|
gptkb:tissue_plasminogen_activator
gptkb:enzyme
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
gptkb:B01AD01
|
|
gptkbp:CASNumber
|
9002-01-1
|
|
gptkbp:category
|
fibrinolytic drug
|
|
gptkbp:contraindication
|
active bleeding
recent surgery
history of hemorrhagic stroke
|
|
gptkbp:discoveredBy
|
William S. Tillett
|
|
gptkbp:discoveredIn
|
1933
|
|
gptkbp:eliminationHalfLife
|
23 minutes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Streptokinase
|
|
gptkbp:KEGGID
|
D08409
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
activates plasminogen
converts plasminogen to plasmin
|
|
gptkbp:MeSH_ID
|
D013292
|
|
gptkbp:molecularWeight
|
~47 kDa
|
|
gptkbp:notRecommendedFor
|
children
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:producedBy
|
gptkb:Streptococcus_bacteria
|
|
gptkbp:PubChem_CID
|
DB00086
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
bleeding
allergic reactions
|
|
gptkbp:UNII
|
ECM4QQF0G5
|
|
gptkbp:usedFor
|
treatment of deep vein thrombosis
treatment of pulmonary embolism
treatment of myocardial infarction
dissolving blood clots
|
|
gptkbp:bfsParent
|
gptkb:Thrombolytics
|
|
gptkbp:bfsLayer
|
7
|