Statements (34)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:Specificity_protein_3
Transcription factor Sp3 |
gptkbp:binds |
GC-rich motifs
|
gptkbp:domain |
zinc finger domain
transactivation domain repression domain |
gptkbp:encodedBy |
gptkb:SP3_gene
|
gptkbp:expressedIn |
various tissues
|
gptkbp:family |
gptkb:Sp/KLF_family
|
gptkbp:function |
transcription factor
|
gptkbp:hasIsoform |
multiple
|
https://www.w3.org/2000/01/rdf-schema#label |
Sp3 protein
|
gptkbp:interactsWith |
gptkb:Sp1_protein
co-activators histone deacetylases |
gptkbp:locale |
gptkb:nucleus
|
gptkbp:locatedOnChromosome |
2q31-q32
|
gptkbp:molecularWeight |
~90 kDa
|
gptkbp:OMIM |
601722
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:postTranslationalModification |
phosphorylation
sumoylation acetylation |
gptkbp:regulates |
apoptosis
differentiation gene expression cell growth immune response cell cycle promoters with GC boxes |
gptkbp:UniProtID |
Q02447
|
gptkbp:bfsParent |
gptkb:SP3_gene
|
gptkbp:bfsLayer |
8
|