Simvastatin

GPTKB entity

Properties (49)
Predicate Object
gptkbp:instanceOf statin
gptkbp:ageLimit not recommended for children under 10
gptkbp:approves gptkb:FDA
gptkbp:availableSizes 10 mg
5 mg
20 mg
80 mg
40 mg
gptkbp:brand gptkb:Zocor
gptkbp:chemicalFormula C25H38O5
gptkbp:class HMG-CoA reductase inhibitor
gptkbp:contraindication allergic reactions
pregnancy
breastfeeding
cognitive impairment
active liver disease
rhabdomyolysis
gptkbp:developedBy gptkb:Merck_&_Co.
gptkbp:dosageForm oral tablet
gptkbp:formulation tablet
gptkbp:healthcare regular exercise
avoid alcohol
consult doctor before starting new medications
maintain a healthy diet
report unexplained muscle pain
https://www.w3.org/2000/01/rdf-schema#label Simvastatin
gptkbp:interactsWith certain antibiotics
antifungal medications
grapefruit juice
gptkbp:is_monitored_by liver function tests
lipid levels
gptkbp:isATypeOf 79902-63-9
gptkbp:lastProduced 1991
gptkbp:legalStatus prescription only
gptkbp:mandates hyperlipidemia
prevent cardiovascular disease
gptkbp:marketedAs gptkb:Zocor
gptkbp:numberOfStudents 2 to 3 hours
gptkbp:nutritionalValue liver
gptkbp:operates_in C10AA01
gptkbp:route oral
gptkbp:sideEffect muscle pain
liver damage
digestive problems
increased blood sugar
gptkbp:triggerType inhibits HMG-CoA reductase
gptkbp:usedFor lowering cholesterol
gptkbp:waterManagement bile
gptkbp:weight 418.57 g/mol