Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
CAMKK2 inhibitor |
| gptkbp:application |
cell signaling studies
pharmacological tool |
| gptkbp:CASNumber |
52029-86-4
|
| gptkbp:chemicalFormula |
C20H13N3O4S
|
| gptkbp:criteria |
more selective for CaMKK2 than CaMKK1
|
| gptkbp:effect |
affects glucose metabolism
blocks CaMKK2-mediated phosphorylation of AMPK modulates energy homeostasis |
| https://www.w3.org/2000/01/rdf-schema#label |
STO-609
|
| gptkbp:inhibitedBy |
gptkb:CaMKK1
|
| gptkbp:IUPACName |
7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid
|
| gptkbp:mechanismOfAction |
inhibits Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2)
|
| gptkbp:molecularWeight |
391.4 g/mol
|
| gptkbp:solubility |
gptkb:DMSO
|
| gptkbp:studiedBy |
gptkb:AMPK_pathway
cancer biology metabolic regulation |
| gptkbp:synonym |
STO609
|
| gptkbp:target |
gptkb:CaMKK2
|
| gptkbp:bfsParent |
gptkb:CAMKK2
gptkb:CaMKIV |
| gptkbp:bfsLayer |
8
|