|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
D12S1644
STAT6A
STAT6B
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:atopic_dermatitis
asthma
allergic diseases
|
|
gptkbp:biologicalProcess
|
immune response
DNA binding
transcriptional activator activity
cytokine-mediated signaling pathway
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredBy
|
gptkb:Darnell_lab
|
|
gptkbp:encodes
|
gptkb:Signal_transducer_and_activator_of_transcription_6
|
|
gptkbp:Entrez_Gene_ID
|
6778
|
|
gptkbp:expressedIn
|
immune cells
|
|
gptkbp:firstDescribed
|
1996
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
11366
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
STAT6 gene
|
|
gptkbp:involvedIn
|
IL-13 signaling pathway
IL-4 signaling pathway
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12
12q13.3
|
|
gptkbp:OMIM
|
601512
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Stat6
|
|
gptkbp:phosphorylates
|
tyrosine 641
|
|
gptkbp:product
|
STAT6 protein
|
|
gptkbp:regulates
|
IgE class switching
Th2 cell differentiation
|
|
gptkbp:UniProtID
|
gptkb:P42226
|
|
gptkbp:bfsParent
|
gptkb:STAT6
|
|
gptkbp:bfsLayer
|
8
|