STAT3 signaling pathway

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf signaling molecule
gptkbp:activatedBy cytokines
growth factors
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
inflammation
gptkbp:cause gene transcription
gptkbp:discoveredBy 1994
https://www.w3.org/2000/01/rdf-schema#label STAT3 signaling pathway
gptkbp:inhibitedBy gptkb:SOCS3
gptkb:PIAS3
gptkbp:involves dimerization
phosphorylation
nuclear translocation
gptkbp:involvesProtein gptkb:JAK
gptkb:STAT3
gptkbp:regulates cell proliferation
cell survival
immune response
gptkbp:targetOfDrug gptkb:Stattic
Napabucasin
gptkbp:bfsParent gptkb:vIL-6
gptkbp:bfsLayer 7