|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
3-oxo-5-alpha-steroid 4-dehydrogenase 1
SR type 1
steroid 5-alpha-reductase 1
|
|
gptkbp:associatedWith
|
gptkb:polycystic_ovary_syndrome
prostate cancer
androgen metabolism
|
|
gptkbp:biologicalProcess
|
oxidoreductase activity
steroid biosynthetic process
|
|
gptkbp:encodes
|
steroid 5 alpha-reductase 1
|
|
gptkbp:Entrez_Gene_ID
|
6715
ENSG00000163207
|
|
gptkbp:enzymeCommissionNumber
|
1.3.1.22
|
|
gptkbp:expressedIn
|
gptkb:skin
gptkb:prostate
brain
liver
|
|
gptkbp:function
|
catalyzes conversion of testosterone to dihydrotestosterone
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11288
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SRD5A1
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
|
|
gptkbp:mutationAssociatedWith
|
5-alpha-reductase deficiency
|
|
gptkbp:OMIM
|
184705
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Srd5a1
|
|
gptkbp:subcellularLocation
|
endoplasmic reticulum membrane
|
|
gptkbp:UniProtID
|
P18405
|
|
gptkbp:bfsParent
|
gptkb:5α-reductase
|
|
gptkbp:bfsLayer
|
8
|