Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
3-oxo-5-alpha-steroid 4-dehydrogenase 1
SR type 1 steroid 5-alpha-reductase 1 |
| gptkbp:associatedWith |
gptkb:polycystic_ovary_syndrome
prostate cancer androgen metabolism |
| gptkbp:biologicalProcess |
oxidoreductase activity
steroid biosynthetic process |
| gptkbp:encodes |
steroid 5 alpha-reductase 1
|
| gptkbp:Entrez_Gene_ID |
6715
ENSG00000163207 |
| gptkbp:enzymeCommissionNumber |
1.3.1.22
|
| gptkbp:expressedIn |
gptkb:skin
gptkb:prostate brain liver |
| gptkbp:function |
catalyzes conversion of testosterone to dihydrotestosterone
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
11288
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_5
|
| gptkbp:mutationAssociatedWith |
5-alpha-reductase deficiency
|
| gptkbp:OMIM |
184705
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Srd5a1
|
| gptkbp:subcellularLocation |
endoplasmic reticulum membrane
|
| gptkbp:UniProtID |
P18405
|
| gptkbp:bfsParent |
gptkb:5α-reductase
|
| gptkbp:bfsLayer |
8
|
| http://www.w3.org/2000/01/rdf-schema#label |
SRD5A1
|