Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activity |
phosphorylation of tyrosine residues
|
| gptkbp:alsoKnownAs |
gptkb:Src_family_kinases
|
| gptkbp:discoveredBy |
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop |
| gptkbp:domain |
SH2 domain
SH3 domain tyrosine kinase domain |
| gptkbp:foundIn |
gptkb:metazoans
|
| gptkbp:function |
non-receptor tyrosine kinases
|
| https://www.w3.org/2000/01/rdf-schema#label |
SRC family
|
| gptkbp:member |
gptkb:BLK
gptkb:HCK gptkb:SRC gptkb:LCK gptkb:YRK gptkb:LYN gptkb:FGR FYN YES1 |
| gptkbp:mutationAssociatedWith |
oncogenesis
|
| gptkbp:namedAfter |
gptkb:Rous_sarcoma_virus
|
| gptkbp:orthologIn |
invertebrates
vertebrates |
| gptkbp:regulates |
autoinhibition
phosphorylation |
| gptkbp:role |
cell differentiation
cell survival cell growth cellular signaling cancer development |
| gptkbp:bfsParent |
gptkb:Src_family_kinases
|
| gptkbp:bfsLayer |
7
|