Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
SPRY-2
hSPRY2 sprouty homolog 2 (Drosophila) |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:Noonan_syndrome |
| gptkbp:encodes |
Sprouty homolog 2
|
| gptkbp:Entrez_Gene_ID |
ENSG00000136158
10253 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
sprouty RTK signaling antagonist 2
|
| gptkbp:function |
negative regulator of receptor tyrosine kinase signaling pathways
|
| gptkbp:HGNC_ID |
11270
|
| https://www.w3.org/2000/01/rdf-schema#label |
SPRY2
|
| gptkbp:involvedIn |
apoptosis
differentiation cellular proliferation |
| gptkbp:length |
315 amino acids
|
| gptkbp:locatedOnChromosome |
13q31.1
|
| gptkbp:molecularWeight |
34.6 kDa
|
| gptkbp:mutationAssociatedWith |
can lead to developmental disorders
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Spry2
|
| gptkbp:regulates |
gptkb:MAPK/ERK_pathway
EGF signaling FGF signaling |
| gptkbp:subcellularLocation |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:UniProtID |
O43597
|
| gptkbp:bfsParent |
gptkb:SPRY
|
| gptkbp:bfsLayer |
7
|