Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein
|
| gptkbp:associatedWith |
cancer progression
|
| gptkbp:community |
upregulated in certain tumors
|
| gptkbp:function |
involved in cell adhesion
regulates extracellular matrix |
| gptkbp:geneticDiversity |
gptkb:SPARCL1
|
| gptkbp:hasFunction |
calcium binding
|
| gptkbp:hasPrograms |
gptkb:mouse_SPARCL1
zebrafish sparcl1 rat_SPARCL1 |
| gptkbp:hasRole |
fibrosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
SPARC-like protein 1
|
| gptkbp:influences |
tumor microenvironment
|
| gptkbp:interactsWith |
integrins
|
| gptkbp:involvedIn |
wound healing
angiogenesis |
| gptkbp:isInvolvedIn |
cell differentiation
cell proliferation cell signaling developmental processes immune response metabolic processes signal transduction inflammation cell survival neurogenesis tissue repair tissue remodeling tumor angiogenesis cell apoptosis extracellular signaling angiogenic signaling matrix remodeling angiogenic response cell-cell interactions cell-matrix interactions |
| gptkbp:isLinkedTo |
metastasis
|
| gptkbp:isLocatedIn |
brain
kidney skin heart lung |
| gptkbp:isPartOf |
extracellular matrix
|
| gptkbp:isRegulatedBy |
hypoxia
TGF-beta IL-6 |
| gptkbp:isStudiedIn |
ovarian cancer
lung cancer breast cancer colorectal cancer prostate cancer |
| gptkbp:locatedIn |
human tissues
|
| gptkbp:location |
extracellular space
|
| gptkbp:relatedTo |
gptkb:SPARC_protein
|
| gptkbp:role |
modulates cell migration
|
| gptkbp:technologyDomain |
EF-hand domain
|