|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:SOD1
|
|
gptkbp:cofactor
|
copper
zinc
|
|
gptkbp:discoveredBy
|
gptkb:Irwin_Fridovich
|
|
gptkbp:discoveredIn
|
1969
|
|
gptkbp:EC_number
|
1.15.1.1
|
|
gptkbp:Entrez_Gene_ID
|
6647
|
|
gptkbp:expressedIn
|
most human tissues
|
|
gptkbp:family
|
gptkb:superoxide_dismutase_family
|
|
gptkbp:fullName
|
gptkb:Copper-zinc_superoxide_dismutase
|
|
gptkbp:function
|
catalyzes the dismutation of superoxide radicals
|
|
gptkbp:gene
|
gptkb:SOD1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SOD (Cu-Zn)
|
|
gptkbp:inhibitedBy
|
gptkb:diethyldithiocarbamate
cyanide
|
|
gptkbp:locatedOnChromosome
|
gptkb:human_chromosome_21
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
32 kDa
|
|
gptkbp:mutationAssociatedWith
|
amyotrophic lateral sclerosis
|
|
gptkbp:OMIM
|
147450
|
|
gptkbp:organism
|
found in eukaryotes
|
|
gptkbp:PDB
|
gptkb:1HL5
|
|
gptkbp:product
|
hydrogen peroxide
oxygen
|
|
gptkbp:significance
|
ALS biomarker
oxidative stress protection
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:superoxide_anion
|
|
gptkbp:subunit
|
two identical subunits
|
|
gptkbp:UniProtID
|
gptkb:P00441
|
|
gptkbp:bfsParent
|
gptkb:Cu,Zn-SOD
|
|
gptkbp:bfsLayer
|
7
|