SIRT7 gene

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:SIR2-like_protein_7
gptkb:SIR2L7
gptkbp:associatedWith gptkb:cancer
aging
metabolic regulation
gptkbp:discoveredIn 2000s
gptkbp:encodes Sirtuin 7 protein
gptkbp:Entrez_Gene_ID 51547
ENSG00000187531
gptkbp:expressedIn nucleolus
gptkbp:function regulation of transcription
cellular stress response
histone deacetylation
chromatin remodeling
ribosomal RNA transcription
gptkbp:HGNC_ID gptkb:HGNC:14934
https://www.w3.org/2000/01/rdf-schema#label SIRT7 gene
gptkbp:locatedOnChromosome gptkb:chromosome_17
gptkbp:memberOf sirtuin family
gptkbp:mutationAssociatedWith gptkb:liver_disease
cardiomyopathy
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Sirt7
gptkbp:proteinFamily NAD-dependent deacetylases
gptkbp:regulates RNA polymerase I transcription
gptkbp:UniProtID gptkb:Q9NRC8
gptkbp:bfsParent gptkb:SIRT7
gptkbp:bfsLayer 8