Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affiliatedWith |
AMP-activated protein kinase (AMPK) family
|
| gptkbp:discoveredBy |
T. Sasaki et al.
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:firstDescribed |
1999
|
| gptkbp:fullName |
Salt-inducible kinase family proteins
|
| gptkbp:function |
serine/threonine kinase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
SIK family proteins
|
| gptkbp:involvedIn |
signal transduction
transcriptional regulation cellular metabolism regulation |
| gptkbp:member |
SIK1
SIK2 SIK3 |
| gptkbp:modulatedBy |
PKA
cAMP signaling LKB1 kinase |
| gptkbp:orthologIn |
gptkb:human
gptkb:mouse right |
| gptkbp:phosphorylates |
class IIa histone deacetylases (HDACs)
|
| gptkbp:regulates |
lipid metabolism
gluconeogenesis CREB-mediated gene expression |
| gptkbp:relatedTo |
gptkb:cancer
inflammation metabolic diseases |
| gptkbp:bfsParent |
gptkb:STK11
|
| gptkbp:bfsLayer |
7
|