SH3

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:binds proline-rich motifs
gptkbp:discoveredIn 1988
gptkbp:foundIn gptkb:Src_family_kinases
gptkb:Crk
gptkb:Grb2
signal transduction proteins
eukaryotic proteins
Abl kinase
Nck
p85 subunit of PI3K
gptkbp:fullName Src Homology 3 domain
gptkbp:function mediates protein-protein interactions
gptkbp:GO_term GO:0017124
https://www.w3.org/2000/01/rdf-schema#label SH3
gptkbp:importantFor cell signaling
cytoskeletal organization
endocytosis
cellular localization of proteins
gptkbp:InterPro IPR001452
gptkbp:length about 60 amino acids
gptkbp:proteinFamily PF00018
gptkbp:relatedTo SH2 domain
gptkbp:SCOP 1shf
gptkbp:structure beta-barrel
gptkbp:bfsParent gptkb:Handheld_PC
gptkb:Windows_CE_3.0
gptkb:Windows_Mobile_Standard
gptkb:Windows_CE_2.11
gptkb:Safe_Host
gptkb:World_Para_Shooting
gptkbp:bfsLayer 7