Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:type_2_diabetes |
| gptkbp:discoveredBy |
1998
|
| gptkbp:domain |
Netrin (NTR) domain
frizzled (Fz) domain |
| gptkbp:encodedBy |
SFRP4 gene
|
| gptkbp:Entrez_Gene_ID |
ENSG00000152583
|
| gptkbp:expressedIn |
gptkb:endometrium
gptkb:prostate gptkb:testis adipose tissue pancreas |
| gptkbp:fullName |
Secreted frizzled-related protein 4
|
| gptkbp:function |
modulates Wnt signaling pathway
acts as a Wnt antagonist |
| gptkbp:gene |
gptkb:SFRP4
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
10778
|
| https://www.w3.org/2000/01/rdf-schema#label |
SFRP4
|
| gptkbp:length |
346 amino acids
|
| gptkbp:locatedOnChromosome |
7p14.1
|
| gptkbp:location |
secreted
|
| gptkbp:molecularWeight |
39 kDa
|
| gptkbp:OMIM |
604568
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Sfrp4
|
| gptkbp:PDB |
2QHZ
|
| gptkbp:RefSeq |
NM_003014
|
| gptkbp:regulates |
apoptosis
cell differentiation cell growth |
| gptkbp:UniProtID |
Q6FHJ7
|
| gptkbp:bfsParent |
gptkb:TCF/LEF
|
| gptkbp:bfsLayer |
7
|