SDHA gene

URI: https://gptkb.org/entity/SDHA_gene

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:gene
gptkbp:associatedWith	gptkb:Leigh_syndrome gptkb:pheochromocytoma gptkb:mitochondrial_complex_II_deficiency gptkb:paraganglioma
gptkbp:component	gptkb:succinate_dehydrogenase_complex
gptkbp:encodes	gptkb:SDHA_protein
gptkbp:Entrez_Gene_ID	6389
gptkbp:expressedIn	mitochondria
gptkbp:fullName	gptkb:succinate_dehydrogenase_complex_flavoprotein_subunit_A
gptkbp:function	catalyzes oxidation of succinate to fumarate in the citric acid cycle
gptkbp:HGNC_ID	gptkb:HGNC:10680
gptkbp:inheritance	autosomal recessive
gptkbp:locatedOnChromosome	gptkb:chromosome_5 gptkb:5p15.33
gptkbp:mutationAssociatedWith	mitochondrial respiratory chain complex II deficiency
gptkbp:OMIM	600857
gptkbp:orthologInMouse	gptkb:Sdhd
gptkbp:orthologInYeast	SDH1
gptkbp:UniProtID	gptkb:P31040
gptkbp:bfsParent	gptkb:Hereditary_paraganglioma-pheochromocytoma_syndrome gptkb:SDHA_protein gptkb:hereditary_paraganglioma-pheochromocytoma_syndrome gptkb:hereditary_paraganglioma-pheochromocytoma_syndromes gptkb:succinate-coenzyme_Q_reductase
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	SDHA gene