succinate dehydrogenase complex

URI: https://gptkb.org/entity/succinate_dehydrogenase_complex
GPTKB entity
Statements (38)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:Complex_II
gptkb:succinate-coenzyme_Q_reductase
gptkbp:catalyzes succinate to fumarate
gptkbp:cofactor gptkb:FAD
gptkb:heme_b
iron-sulfur clusters
gptkbp:EC_number 1.3.5.1
gptkbp:electronAcceptor ubiquinone
gptkbp:electronDonor succinate
gptkbp:foundIn prokaryotes
eukaryotes
gptkbp:gene gptkb:SDHA
gptkb:SDHB
gptkb:SDHC
gptkb:SDHD
gptkbp:GO GO:0008177
gptkbp:hasComponent gptkb:SDHA
gptkb:SDHB
gptkb:SDHC
gptkb:SDHD
https://www.w3.org/2000/01/rdf-schema#label succinate dehydrogenase complex
gptkbp:inhibitedBy gptkb:thenoyltrifluoroacetone
malonate
gptkbp:locatedIn inner mitochondrial membrane
gptkbp:mutationAssociatedWith gptkb:Leigh_syndrome
gptkb:pheochromocytoma
paraganglioma
gptkbp:OMIM 600857
gptkbp:partOf electron transport chain
citric acid cycle
gptkbp:PDB 1ZOY
gptkbp:product fumarate
gptkbp:substrate succinate
gptkbp:UniProtID Q967G6
gptkbp:bfsParent gptkb:Q99643_(SDHC,_human)
gptkb:mitochondrial_complex_II_deficiency
gptkbp:bfsLayer 7