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gptkbp:instanceOf
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gptkb:enzyme
|
|
gptkbp:activatedBy
|
Rubisco activase
|
|
gptkbp:activity
|
slow turnover rate (~3 s⁻¹)
|
|
gptkbp:alternativeName
|
form I
form II
form III
form IV
|
|
gptkbp:biotechnologicalInterest
|
target for improving crop yield
|
|
gptkbp:cofactor
|
Mg2+
|
|
gptkbp:discoveredBy
|
gptkb:Melvin_Calvin
|
|
gptkbp:EC_number
|
4.1.1.39
|
|
gptkbp:evolvesFrom
|
ancient enzyme, present in early photosynthetic organisms
|
|
gptkbp:foundIn
|
gptkb:algae
gptkb:Bacteria
plants
|
|
gptkbp:fullName
|
gptkb:Ribulose-1,5-bisphosphate_carboxylase/oxygenase
|
|
gptkbp:function
|
catalyzes the first major step of carbon fixation
|
|
gptkbp:gene
|
gptkb:rbcL_(large_subunit)
gptkb:rbcS_(small_subunit)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rubisco
|
|
gptkbp:importantFor
|
most abundant protein on Earth
|
|
gptkbp:inhibitedBy
|
gptkb:2-carboxyarabinitol_1-phosphate
|
|
gptkbp:involvedIn
|
gptkb:Calvin_cycle
photorespiration
|
|
gptkbp:limitation
|
low catalytic efficiency
oxygenase activity leads to photorespiration
|
|
gptkbp:location
|
chloroplast
|
|
gptkbp:molecularWeight
|
~550 kDa (form I holoenzyme)
|
|
gptkbp:optimum_pH
|
~8
|
|
gptkbp:PDB
|
gptkb:1RCX
|
|
gptkbp:presentIn
|
gptkb:C3_plants
gptkb:C4_plants
gptkb:CAM_plants
|
|
gptkbp:product
|
gptkb:3-phosphoglycerate
2-phosphoglycolate
|
|
gptkbp:regulates
|
activated by CO2 and Mg2+
inhibited by sugar phosphates
|
|
gptkbp:structure
|
hexadecamer (8 large and 8 small subunits in form I)
|
|
gptkbp:studiedIn
|
gptkb:Chlamydomonas_reinhardtii
gptkb:Arabidopsis_thaliana
Oryza sativa (rice)
Zea mays (maize)
Spinacia oleracea (spinach)
|
|
gptkbp:substrate
|
oxygen
carbon dioxide
ribulose-1,5-bisphosphate
|
|
gptkbp:subunit
|
large subunit encoded by chloroplast genome
small subunit encoded by nuclear genome
|
|
gptkbp:type
|
carboxylation
oxygenation
|
|
gptkbp:bfsParent
|
gptkb:Chloroplast
|
|
gptkbp:bfsLayer
|
6
|