Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
cell signaling
cytoskeletal organization |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:foundIn |
gptkb:BCR_protein
gptkb:p190_RhoGAP ARHGAP family proteins DLC1 protein OCRL protein Rho GTPase-activating proteins |
| gptkbp:function |
stimulates GTPase activity of Rho family proteins
|
| gptkbp:GO_term |
GTPase activator activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
RhoGAP domain
|
| gptkbp:InterPro |
IPR000198
|
| gptkbp:length |
~150 amino acids
|
| gptkbp:mechanismOfAction |
promotes hydrolysis of GTP to GDP on Rho GTPases
|
| gptkbp:proteinFamily |
PF00620
|
| gptkbp:regulates |
gptkb:Rho_GTPases
|
| gptkbp:relatedTo |
RasGAP domain
Rho GTPase |
| gptkbp:structure |
contains conserved arginine finger
|
| gptkbp:bfsParent |
gptkb:RhoGAP
|
| gptkbp:bfsLayer |
7
|