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gptkbp:instanceOf
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gptkb:nuclear_receptor
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gptkbp:abbreviation
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gptkb:RXR
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gptkbp:activatedBy
|
ligand binding
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gptkbp:actsOn
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gptkb:transcription_factor
|
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gptkbp:binds
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gptkb:9-cis-retinoic_acid
|
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gptkbp:discoveredBy
|
1990
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gptkbp:domain
|
DNA-binding domain
ligand-binding domain
|
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gptkbp:encodedBy
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RXRA gene
RXRB gene
RXRG gene
|
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gptkbp:expressedIn
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gptkb:adipose_tissue
gptkb:skin
gptkb:skeletal_muscle
brain
liver
|
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gptkbp:formsHeterodimerWith
|
Peroxisome Proliferator-Activated Receptor
Retinoic Acid Receptor
Thyroid Hormone Receptor
Vitamin D Receptor
|
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gptkbp:foundIn
|
vertebrates
|
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gptkbp:gene
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gptkb:RXR
|
|
gptkbp:hasIsoform
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gptkb:RXR_alpha
gptkb:RXR_beta
gptkb:RXR_gamma
|
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gptkbp:involves
|
apoptosis
cell differentiation
development
metabolism
|
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gptkbp:locatedIn
|
cell nucleus
|
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gptkbp:member
|
nuclear receptor superfamily
|
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gptkbp:molecularWeight
|
~50 kDa
|
|
gptkbp:PDB
|
1FBY
1LBD
1MV9
|
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gptkbp:regulates
|
cell proliferation
gene expression
lipid metabolism
glucose metabolism
inflammatory response
|
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gptkbp:target
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gptkb:rexinoids
gptkb:bexarotene
LGD1069
LG100268
|
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gptkbp:UniProtID
|
P19793
P28702
P48443
|
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gptkbp:bfsParent
|
gptkb:Liver_X_Receptor
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Retinoid X Receptor
|