Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
nuclear receptor
|
| gptkbp:abbreviation |
gptkb:RXR
|
| gptkbp:activatedBy |
ligand binding
|
| gptkbp:actsOn |
transcription factor
|
| gptkbp:binds |
gptkb:9-cis-retinoic_acid
|
| gptkbp:discoveredBy |
1990
|
| gptkbp:domain |
DNA-binding domain
ligand-binding domain |
| gptkbp:encodedBy |
RXRA gene
RXRB gene RXRG gene |
| gptkbp:expressedIn |
gptkb:skin
gptkb:skeletal_muscle brain liver adipose tissue |
| gptkbp:formsHeterodimerWith |
Peroxisome Proliferator-Activated Receptor
Retinoic Acid Receptor Thyroid Hormone Receptor Vitamin D Receptor |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:gene |
gptkb:RXR
|
| gptkbp:hasIsoform |
gptkb:RXR_alpha
gptkb:RXR_beta gptkb:RXR_gamma |
| https://www.w3.org/2000/01/rdf-schema#label |
Retinoid X Receptor
|
| gptkbp:involves |
apoptosis
cell differentiation development metabolism |
| gptkbp:locatedIn |
cell nucleus
|
| gptkbp:member |
nuclear receptor superfamily
|
| gptkbp:molecularWeight |
~50 kDa
|
| gptkbp:PDB |
1FBY
1LBD 1MV9 |
| gptkbp:regulates |
cell proliferation
gene expression lipid metabolism glucose metabolism inflammatory response |
| gptkbp:target |
gptkb:rexinoids
gptkb:bexarotene LGD1069 LG100268 |
| gptkbp:UniProtID |
P19793
P28702 P48443 |
| gptkbp:bfsParent |
gptkb:Liver_X_Receptor
|
| gptkbp:bfsLayer |
7
|