Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
guanine nucleotide exchange factors
|
| gptkbp:binds |
gptkb:GDP
gptkb:GTP |
| gptkbp:decommissioned |
GTPase-activating proteins
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
molecular switch
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ras-like GTPases
|
| gptkbp:includes |
gptkb:Ras_proteins
Arf proteins Rab proteins Ran proteins Rho proteins |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:regulates |
cell differentiation
cell proliferation cell survival vesicle trafficking cell migration |
| gptkbp:structure |
G domain
|
| gptkbp:subclassOf |
guanine nucleotide exchange factor
|
| gptkbp:bfsParent |
gptkb:P-loop_NTPase_superfamily
|
| gptkbp:bfsLayer |
7
|