Rap guanine nucleotide exchange factor 3
GPTKB entity
Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:cAMP
gptkb:Rap1 gptkb:Rap2 |
| gptkbp:alsoKnownAs |
gptkb:Epac1
|
| gptkbp:associatedWith |
cell adhesion
cell junction formation insulin secretion neuronal signaling cardiac function |
| gptkbp:discoveredBy |
1998
|
| gptkbp:domain |
Ras-GEF domain
cAMP-binding domain |
| gptkbp:encodedBy |
RAPGEF3 gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000139132
GC12M053282 |
| gptkbp:function |
gptkb:guanine_nucleotide_exchange_factor
|
| gptkbp:gene |
gptkb:RAPGEF3
|
| gptkbp:HGNC_ID |
HGNC:4567
|
| gptkbp:involves |
gptkb:cAMP_signaling_pathway
signal transduction |
| gptkbp:locatedOnChromosome |
12q13.11
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
104 kDa
|
| gptkbp:OMIM |
605197
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Rapgef3
|
| gptkbp:PDB |
2BYV
|
| gptkbp:RefSeq |
NM_006663
|
| gptkbp:UniProtID |
O95398
|
| gptkbp:bfsParent |
gptkb:RAPGEF3
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Rap guanine nucleotide exchange factor 3
|