Ran GTPases

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:binds gptkb:GDP
gptkb:GTP
gptkbp:discoveredIn 1990
gptkbp:encodedBy gptkb:RAN_gene
gptkbp:foundIn eukaryotic cells
gptkbp:function mitotic spindle assembly
nuclear envelope formation
regulation of nucleocytoplasmic transport
https://www.w3.org/2000/01/rdf-schema#label Ran GTPases
gptkbp:interactsWith gptkb:importin_beta
RanGEF
RanGAP
exportin 1
gptkbp:locale gptkb:nucleus
gptkb:cytoplasm
gptkbp:memberOf gptkb:Ras_superfamily
gptkbp:molecularWeight ~24 kDa
gptkbp:orthologIn yeast Gsp1
gptkbp:regulates GTP hydrolysis
exportin-mediated nuclear export
guanine nucleotide exchange
importin-mediated nuclear import
gptkbp:relatedTo cell cycle
chromosome segregation
nuclear transport receptors
gptkbp:structure G domain
gptkbp:subclassOf small molecule
gptkbp:bfsParent gptkb:Ras_superfamily_GEFs
gptkbp:bfsLayer 7