|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:administeredBy
|
gptkb:misoprostol
|
|
gptkbp:alsoKnownAs
|
gptkb:mifepristone
|
|
gptkbp:approvalYear
|
1988
|
|
gptkbp:approvedBy
|
gptkb:China
gptkb:France
gptkb:India
gptkb:United_Kingdom
gptkb:United_States
|
|
gptkbp:ATCCode
|
G03XB01
|
|
gptkbp:CASNumber
|
gptkb:84371-65-3
|
|
gptkbp:chemicalClass
|
gptkb:Corticosteroid
|
|
gptkbp:contraindication
|
bleeding disorders
ectopic pregnancy
long-term corticosteroid therapy
chronic adrenal failure
|
|
gptkbp:cost
|
varies by country
|
|
gptkbp:developedBy
|
Roussel Uclaf
|
|
gptkbp:discoveredBy
|
Émile-Étienne Baulieu
|
|
gptkbp:discoveredIn
|
1980
|
|
gptkbp:hasMolecularFormula
|
gptkb:C29H35NO2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RU486
|
|
gptkbp:legalStatus
|
varies by country
prescription only
|
|
gptkbp:marketedAs
|
gptkb:Sun_Pharma
gptkb:Zydus_Cadila
Danco Laboratories
Exelgyn
HLL Lifecare
Linepharma
|
|
gptkbp:mechanismOfAction
|
progesterone receptor antagonist
|
|
gptkbp:molecularWeight
|
429.6 g/mol
|
|
gptkbp:patent
|
Roussel Uclaf
|
|
gptkbp:pregnancyCategory
|
X (contraindicated in pregnancy except for abortion)
|
|
gptkbp:prescribes
|
termination of intrauterine pregnancy
Cushing's syndrome (off-label)
cervical ripening
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
vomiting
diarrhea
bleeding
dizziness
headache
cramping
|
|
gptkbp:usedFor
|
oral contraceptive
medical abortion
management of miscarriage
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:House_of_Gold_&_Bones_–_Part_1
|
|
gptkbp:bfsLayer
|
7
|