|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:S6
gptkb:ribosomal_protein_S6
|
|
gptkbp:associatedWith
|
cell proliferation
cell growth
translation regulation
|
|
gptkbp:discoveredBy
|
1970s
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000137154
|
|
gptkbp:fullName
|
40S ribosomal protein S6
|
|
gptkbp:function
|
involved in protein synthesis
component of the 40S ribosomal subunit
|
|
gptkbp:gene
|
gptkb:RPS6
|
|
gptkbp:GO
|
GO:0003735 (structural constituent of ribosome)
GO:0006412 (translation)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RPS6
|
|
gptkbp:locatedOnChromosome
|
gptkb:9p21
chromosome 9: 45,156,000-45,159,000 (GRCh38)
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
28 kDa
|
|
gptkbp:mutationAssociatedWith
|
can affect protein synthesis
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
present in many eukaryotes
|
|
gptkbp:pathway
|
gptkb:mTOR_signaling_pathway
translation initiation
|
|
gptkbp:PDB
|
4V6X
|
|
gptkbp:phosphorylates
|
regulated by S6 kinases
regulated by mTOR pathway
|
|
gptkbp:RefSeq
|
NP_001001
|
|
gptkbp:structure
|
contains multiple phosphorylation sites
|
|
gptkbp:UniProtID
|
P62753
|
|
gptkbp:bfsParent
|
gptkb:Ribosomal_proteins
gptkb:ribosomal_protein_S6
|
|
gptkbp:bfsLayer
|
7
|