RNase L

GPTKB entity

Statements (60)
Predicate Object
gptkbp:instance_of gptkb:award
gptkbp:associated_with gptkb:Oncology
gptkb:neurodegenerative_diseases
gptkbp:discovered_by 1990s
gptkbp:function degrades RNA
gptkbp:fuselage_material viral RNA
https://www.w3.org/2000/01/rdf-schema#label RNase L
gptkbp:inhibition_effects viral replication
gptkbp:initiated_by double-stranded RNA
2-5 A
RNase L inhibitor (RLI)
RNase L inhibitor protein
gptkbp:interacts_with gptkb:RNA_Polymerase
gptkbp:involved_in RNA interference
RNA metabolism
cellular homeostasis
cellular metabolism
cellular stress response
immune response
cellular differentiation
RNA processing
cellular signaling pathways
cellular signaling
innate immunity
cellular repair mechanisms
cellular signaling cascades
immune evasion
viral pathogenesis
protein synthesis regulation
cellular homeostatic mechanisms
cellular signaling networks
cellular regulation
cellular growth regulation
cellular apoptosis
cellular apoptosis pathways
cellular defense mechanisms
cellular stress response pathways
stress granule formation
translational control
cytokine signaling
cellular immune response
RNA surveillance
apoptotic signaling
antiviral response
host defense mechanisms
interferon signaling
cellular defense responses
cellular signaling pathways involved in apoptosis
m RNA degradation
viral RNA degradation
viral infection response
gptkbp:is_expressed_in gptkb:Cell
gptkbp:location cytoplasm
gptkbp:pathway 2-5 A pathway
gptkbp:produced_by gptkb:Interpol
gptkbp:promoter RNASEL
gptkbp:related_to 2-5 A synthetase
gptkbp:role regulating apoptosis
gptkbp:bfsParent gptkb:OAS_complex
gptkbp:bfsLayer 8